USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: PYRG1_HUMAN USC-OGP 2-DE database:  PYRG1_HUMAN PYRG1_HUMAN General information about the entry View entry in simple text format Entry name PYRG1_HUMAN Primary accession number P17812 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=CTP synthase 1 {ECO:0000305}; EC=6.3.4.2 {ECO:0000269|PubMed:16179339, ECO:0000269|PubMed:24870241}; AltName: Full=CTP synthetase 1; AltName: Full=UTP--ammonia ligase 1;. Gene name Name=CTPS1 {ECO:0000312|HGNC:HGNC:2519} Synonyms=CTPS {ECO:0000312|HGNC:HGNC:2519} Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1120: pI=6.09; Mw=84978 SPOT OGP-1122: pI=6.30; Mw=81577 SPOT OGP-1150: pI=6.41; Mw=55186 Cross-references UniProtKB/Swiss-Prot P17812; PYRG1_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name PYRG1_HUMAN Primary accession number P17812 Secondary accession number(s) B4DR64 D3DPW1 Q5VW67 Q96GK6 Sequence was last modified on  May 15, 2002 (version 2) Annotations were last modified on  March 15, 2017 (version 183) Name and origin of the protein Description RecName: Full=CTP synthase 1 {ECO:0000305}; EC=6.3.4.2 {ECO:0000269|PubMed:16179339, ECO:0000269|PubMed:24870241}; AltName: Full=CTP synthetase 1; AltName: Full=UTP--ammonia ligase 1; Gene name Name=CTPS1 {ECO:0000312|HGNC:HGNC:2519} Synonyms=CTPS {ECO:0000312|HGNC:HGNC:2519} Encoded on Name=CTPS1 {ECO:0000312|HGNC:HGNC:2519}; Synonyms=CTPS {ECO:0000312|HGNC:HGNC:2519 Keywords 3D-structure; Acetylation; Alternative splicing; ATP-binding; Complete proteome; Glutamine amidotransferase; Immunity; Ligase; Nucleotide-binding; Phosphoprotein; Polymorphism; Pyrimidine biosynthesis; Reference proteome. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL X52142; CAA36386.1; -; mRNA EMBL AK299122; BAG61176.1; -; mRNA EMBL AL391730; CAH72797.1; -; Genomic_DNA EMBL CH471059; EAX07192.1; -; Genomic_DNA EMBL CH471059; EAX07193.1; -; Genomic_DNA EMBL BC009408; AAH09408.1; -; mRNA CCDS CCDS459.1; -. [P17812-1]; . PIR S12791; SYHUTP; . RefSeq NP_001288166.1; NM_001301237.1; . RefSeq NP_001896.2; NM_001905.3. [P17812-1]; . UniGene Hs.473087; -; . PDB 2VO1; X-ray; 2.80 A; A/B=1-273 PDBsum 2VO1; -; . ProteinModelPortal P17812; -; . SMR P17812; -; . BioGrid 107883; 64; . IntAct P17812; 16; . MINT MINT-3008801; -; . STRING 9606.ENSP00000361699; -; . DrugBank DB00130; L-Glutamine; . MEROPS C26.A36; -; . iPTMnet P17812; -; . PhosphoSitePlus P17812; -; . SwissPalm P17812; -; . BioMuta CTPS1; -; . DMDM 20981706; -; . EPD P17812; -; . MaxQB P17812; -; . PaxDb P17812; -; . PeptideAtlas P17812; -; . PRIDE P17812; -; . Ensembl ENST00000372616; ENSP00000361699; ENSG00000171793. [P17812-1]; . Ensembl ENST00000372621; ENSP00000361704; ENSG00000171793. [P17812-1]; . GeneID 1503; -; . KEGG hsa:1503; -; . UCSC uc001cgk.5; human. [P17812-1]; . CTD 1503; -; . DisGeNET 1503; -; . GeneCards CTPS1; -; . H-InvDB HIX0000479; -; . HGNC HGNC:2519; CTPS1; . HPA CAB017111; -; . HPA HPA051322; -; . MalaCards CTPS1; -; . MIM 123860; gene; . MIM 615897; phenotype; . neXtProt NX_P17812; -; . OpenTargets ENSG00000171793; -; . PharmGKB PA27020; -; . eggNOG KOG2387; Eukaryota; . eggNOG COG0504; LUCA; . GeneTree ENSGT00390000012473; -; . HOGENOM HOG000077514; -; . HOVERGEN HBG002243; -; . InParanoid P17812; -; . KO K01937; -; . OMA SCSERHR; -; . OrthoDB EOG091G03OK; -; . PhylomeDB P17812; -; . TreeFam TF300379; -; . BioCyc MetaCyc:HS10382-MONOMER; -; . Reactome R-HSA-499943; Synthesis and interconversion of nucleotide di- and triphosphates; . SIGNOR P17812; -; . UniPathway UPA00159; UER00277; . EvolutionaryTrace P17812; -; . GeneWiki CTP_synthase_1; -; . GenomeRNAi 1503; -; . PRO PR:P17812; -; . Proteomes UP000005640; Chromosome 1; . Bgee ENSG00000171793; -; . CleanEx HS_CTPS; -; . Genevisible P17812; HS; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0016020; C:membrane; IDA:UniProtKB; . GO GO:0005524; F:ATP binding; IEA:UniProtKB-KW; . GO GO:0003883; F:CTP synthase activity; IDA:UniProtKB; . GO GO:0042802; F:identical protein binding; IPI:IntAct; . GO GO:0044210; P:'de novo' CTP biosynthetic process; IEA:UniProtKB-UniPathway; . GO GO:0042100; P:B cell proliferation; IMP:UniProtKB; . GO GO:0006241; P:CTP biosynthetic process; IDA:UniProtKB; . GO GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW; . GO GO:0006139; P:nucleobase-containing compound metabolic process; TAS:ProtInc; . GO GO:0015949; P:nucleobase-containing small molecule interconversion; TAS:Reactome; . GO GO:0042493; P:response to drug; TAS:ProtInc; . GO GO:0042098; P:T cell proliferation; IMP:UniProtKB; . CDD cd01746; GATase1_CTP_Synthase; 1; . Gene3D 3.40.50.300; -; 1; . Gene3D 3.40.50.880; -; 1; . HAMAP MF_01227; PyrG; 1; . InterPro IPR029062; Class_I_gatase-like; . InterPro IPR004468; CTP_synthase; . InterPro IPR017456; CTP_synthase_N; . InterPro IPR017926; GATASE; . InterPro IPR033828; GATase1_CTP_Synthase; . InterPro IPR027417; P-loop_NTPase; . PANTHER PTHR11550; PTHR11550; 1; . Pfam PF06418; CTP_synth_N; 1; . Pfam PF00117; GATase; 1; . SUPFAM SSF52317; SSF52317; 1; . SUPFAM SSF52540; SSF52540; 1; . TIGRFAMs TIGR00337; PyrG; 1; . PROSITE PS51273; GATASE_TYPE_1; 1; .

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